How to Administer IVIG Safely: A Complete Nursing Checklist
Overview of IVIG Administration
One of the most important nursing tasks is giving intravenous immunoglobulin (IVIG), which calls for accuracy, planning, and attention to detail. In order to ensure the safety and effectiveness of IVIG therapy, which is used to modify the immune response in a variety of medical disorders, nurses are essential frontline caregivers. From pre-infusion evaluations to post-care paperwork, this comprehensive checklist helps nurses at every stage to reduce complications and improve patient outcomes.

Why is IVIG used, and what is it?
A sterile solution of concentrated antibodies taken from a pool of human plasma is called intravenous immunoglobulin (IVIG). It is mostly used to treat autoimmune diseases, immunodeficiency disorders, and some neurological ailments.
Common IIG-Treated Conditions Primary immunodeficiencies (such as X-linked agammaglobulinemia and CVID)
Syndrome Guillain-Barré
Polyneuropathy with chronic inflammation and demyelination (CIDP)
Kawasaki disease
Purpura immune thrombocytopenic (ITP)
Gravis myasthenia
The role of nurses in IVIG therapy: duties before to, during, and following infusion
Check the patient’s identity and the order.
Verify allergies and contraindications.
Get the supplies and medicine ready.
Track the infusion’s progress and control any negative effects.
Inform the patient’s family about what they can expect.
Nursing Pre-Administration Evaluation
Consent and Patient History
Prior to starting IVIG treatment, nurses need to:
Verify your informed consent.
Verify any prior IVIG administration or allergic response history.
Check for thromboembolic risk, dehydration, or renal impairment.
Initial Vital Signs and Lab Work Documentation:
The temperature
Blood pressure
Rate of pulse
Rate of respiration
Initial values of BUN, IgG, and creatinine
Getting Supplies and Equipment Ready for IVIG Infusion Checklist for IVIG vials (store in the refrigerator or at room temperature)
pump for IV infusion
Typical flushes with saline
Device for monitoring vital signs
Emergency medications: corticosteroids, diphenhydramine, and epinephrine
Reconstitution and Management of Drugs
Observe the manufacturer’s instructions.
Swirl gently; do not shake.
Make sure there are no particles and the solution is obvious.
Detailed IVIG Administration Procedure: Initiating the Infusion: Initial Rate and Modification
Start between 0.01 and 0.02 mL/kg/min.
Increase gradually as tolerated every 15–30 minutes.
Never go over the maximum amount advised by the manufacturer.
Vital Signs Monitoring and Patient Reaction Vital signs monitoring:
Throughout the first hour, every fifteen minutes
After that, every 30 minutes
Keep an eye out for indications of:
Fever and chills
A headache
Either hypertension or hypotension
Tightness or rash in the chest
Handling Typical IVIG Adverse Effects
Interventions for Mild Reactions
Reduce the rate, provide water, and use analgesics for headaches, exhaustion, and fever.
Antiemetics may aid with nausea.
Antihistamines should be used for rashes or itching.
Severe Reactions: How to Treat Anaphylaxis Stop the infusion, administer adrenaline, and start the emergency procedure
Aseptic meningitis and thromboembolism: notify right away and seek emergency care.
Records of Documentation and Communication:
Batch number, time, and dosage
Rate modifications
Vital indicators and patient grievances
Nursing interventions
Report any negative consequences to the doctor and pharmacy.
Particular Attention to Elderly and Pediatric Patients
Younger individuals might require more careful observation and lesser quantities.
Renal or cardiac problems are more likely to occur in elderly persons.
Adapt the infusion rate according to tolerance and body weight.
Education of Patients Following IVIG Infusion
Describe any potential delayed adverse effects, such as headaches or exhaustion.
Give instructions on how to stay hydrated, take breaks, and report any discomfort.
Establish a schedule for lab tests and follow-up appointments.
IVIG Therapy Quality and Safety Requirements
Follow hospital guidelines
Observe the CDC and WHO recommendations.
To reduce errors, use checklists and double-verification processes.
FAQ
What is the duration of an IVIG infusion?
Depending on the dosage and the patient’s tolerance, the majority of IVIG infusions last two to six hours.
Are there any significant adverse effects with IVIG?
Yes, while they are uncommon, severe side effects like thrombosis or anaphylaxis can happen. Nursing intervention must be prompt.
Is it appropriate to infuse IVIG at room temperature?
Yes, chills and discomfort can result from cold IVIG. Prior to infusion, always let it get to room temperature.
How do I react if a patient feels constricted in the chest?
As soon as possible, stop the infusion and notify the doctor. Check for heart involvement or indications of anaphylaxis.
After IVIG treatment, may patients drive?
Advise them not to drive or operate machinery for 24 hours if they have any side effects, such as weariness or dizziness.
Is staying hydrated crucial when receiving IVIG therapy?
Indeed, drinking enough water both before and after an infusion improves drug tolerance and helps avoid kidney problems. In
conclusion
Safe IVIG administration necessitates accuracy, attentiveness, and patient-centered treatment. To guarantee the best results, nurses must adhere to established procedures, keep an eye out for issues, and offer continuous assistance. Healthcare providers can safely and confidently administer IVIG therapy by becoming proficient with this nursing checklist.